MTF/SAEMF Toxicology Research Grant - $19,536

"Effect of High-Dose Insulin in a Porcine Model of Amlodipine-Induced Toxicity"

Amlodipine overdose is increasingly common in emergency departments, but there is no clear consensus on which therapies are best to manage it. This pilot study is expected to fill in key gaps in our knowledge of (high-dose insulin) HDI as a therapy for amlodipine poisoning, and will likely be practice changing for the initial emergency treatment of these overdoses.

Recipient(s)

  • Arthur Jurao, MD

    Arthur Jurao, MD

    Hennepin Healthcare Research Institute

    "Effect of High-Dose Insulin in a Porcine Model of Amlodipine-Induced Toxicity"

    Arthur Jurao, MD, is an emergency physician and recently graduated as a medical toxicologist from the HealthPartners Twin Cities Medical Toxicology Fellowship in Minnesota. He earned a Master of Science in biochemistry and graduated from Georgetown University School of Medicine. He then completed an emergency medicine residency at St. John’s Riverside Hospital in Yonkers, New York. Dr. Jurao’s interests in toxicology include a fascination with chemical structure/function relationships and biochemical mechanisms of toxicity. Many of his mentors during toxicology fellowship have notably conducted animal research studying high-dose insulin therapy and were the key inspiration to continue this work as a fellow and beyond. Dr. Jurao hopes to continue his career in academic research in toxicology, and foster research opportunities for the fellows in Minnesota.