2020-21 SAEMF Research Large Project Grant - $150,000

“Psychological Contributors to Cardiovascular Disease Risk in ED Patients”

There is a critical need to identify individuals who are at risk for coronary artery disease (CAD) secondary to anxiety and depression in the ED and define the interplay between the two disease states, so effective interventions aimed at reducing CAD development can be implemented. It has been shown that anxiety and depression symptoms are linked to nitric oxide (NO) mediated, endothelial cell-vascular smooth muscle (EC-VSM) hyporesponsiveness to shear stress.